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Further Information

Ulcerative colitis

Crohn's Disease

Microscopic Colitis

Inflammatory Bowel Diseases

The term “inflammatory bowel disease” (IBD) refers particularly to Ulcerative colitis and Crohn’s Disease. Microscopic colitis (subdivided into collagenous and lymphocytic colitis) has recently been recognized as an IBD. We do not yet have a detailed understanding of the exact cause of the disease. However, a combination of various different factors is involved in the onset of the disease. A key aspect is a failure of the intestinal mucosal barrier function, allowing many harmful substances contained in the gut to penetrate the intestinal mucosa from the gastrointestinal tract. The body’s natural reaction is to trigger an inflammation and defense response from the immune system. Psychological factors such as stress or similar may cause existing symptoms to worsen or exacerbate a pre-existing condition but according to the current state of knowledge they are not directly responsible for the onset of the disease.

Patienten für laufende Studie zu MORBUS CROHN gesucht!

Klinische Studie zur Beurteilung eines neuen, sich in der Erprobung befindlichen biologischen Medikaments. Der Name der Studie ist TRUST-2, was für „TRichUris Suis ova Trial“ steht.

Mehr als 200 Patienten mit MORBUS CROHN haben das sich in der Erprobung befindende Studienmedikament bisher in klinischen Studien eingenommen.

Die Studien zeigen eine Abnahme der Krankheitsaktivität und in der Mehrzahl der Fälle wurde Remission (beschwerdefreie Phase) erzielt. Die bisher beobachteten Nebenwirkungen betrafen zumeist den Verdauungstrakt.