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Further Information

Primary Biliary Cirrhosis/Cholangitis

Primary Sclerosing Cholangitis

Fatty Liver Disease

Hepatitis

Autoimmune Hepatitis

Liver Cirrhosis

Hepatic Encephalopathy

Hepatocellular Carcinoma


Liver Diseases / Diseases of the Liver

Throughout the world and in the course of history, diseases of the liver and bile duct have been common diseases that severely impair quality of life and in some cases life expectancy of those affected. Today they are amongst the most common diseases alongside cardiovascular diseases. In many cases the liver disease has a chronic clinical course, persisting throughout a person’s entire lifetime. Many diseases of the liver will often be asymptomatic or merely present non-specific physical symptoms for years on end. This means that there are frequently no extremely noticeable pathological symptoms to cause alarm to the patient and make him consult a doctor in time.
Constant fatigue, digestive complaints, chronic pruritus or frequent nosebleeds are often dismissed as “everyday complaints” and not taken very seriously as a result. These symptoms may quite possibly be indications of cholestatic liver disease. More obvious signs are jaundice, dark, beer-colored urine, discoloration of stools, reduction in bone density and skin abnormalities. Many chronic liver diseases ultimately lead to cirrhosis. Prevention of cirrhosis with its complications (such as ascites, hepatic encephalopathy or hepatocellular carcinoma) and avoidance of liver transplant are the objectives of all medical therapy.

Diseases of the liver and biliary tract are frequent complaints which have existed since the beginning of time, are known throughout the world and which can have extremely negative effects on quality of life and can also considerably lower the life expectancy of those affected. Nowadays, these disorders are among the most frequent medical conditions, on a part with cardiovascular diseases. In many cases the liver disease becomes chronic and thus persists for life. A large number of liver diseases do not cause any symptoms over many years or there may only be unspecific physical discomfort: noticeable symptoms of disease, which are alarming for the patient and make him/her go straight to the doctor, are therefore missing.
Incessant fatigue, digestive troubles, chronic itching or frequent nosebleeds are often regarded as minor daily problems and are therefore not taken particularly seriously. Such symptoms can definitely be a sign of cholestatic liver disease. More obvious signs are jaundice, urine which is dark and beer-brown in color, discolored stool, reduction in bone density and noticeable skin alterations. Many chronic liver diseases may eventually develop into liver cirrhosis. Avoidance of liver cirrhosis with its complications (e.g. ascites, hepatic encephalopathy or liver cell cancer) or transplantation is the aim of every medicinal therapy.


Patienten für laufende Studie zu MORBUS CROHN gesucht!

Klinische Studie zur Beurteilung eines neuen, sich in der Erprobung befindlichen biologischen Medikaments. Der Name der Studie ist TRUST-2, was für „TRichUris Suis ova Trial“ steht.

Mehr als 200 Patienten mit MORBUS CROHN haben das sich in der Erprobung befindende Studienmedikament bisher in klinischen Studien eingenommen.

Die Studien zeigen eine Abnahme der Krankheitsaktivität und in der Mehrzahl der Fälle wurde Remission (beschwerdefreie Phase) erzielt. Die bisher beobachteten Nebenwirkungen betrafen zumeist den Verdauungstrakt.